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Although they’re technically not a duo, Angela and Leonardo — daughter and son of Pepe Aguilar — are marking their territory in the regional Mexican scene. Both of the talented acts lead their own music careers, but don’t shy away from singing together, especially when they’re on tour with their father.

Brothers Alejandro and Mauricio Rengifo have been going strong as Cali y El Dandee for more than a decade. The Colombian-based duo is known for pop-urban bops such as “Por Fin Te Encontre,” “Locura” and the Danna Paola-assisted “Nada.” Besides singing, the latter is a Latin Grammy producer of the year winner, even co-producing Luis Fonsi’s and Daddy Yankee’s globe-conquering smash “Despacito.”

Known for their sad sierreño and innovative fusions in the música Mexicana realm, including hits like “Ella Baila Sola” with Peso Pluma and “Jugaste y Sufri” with DannyLux, Eslabon Armado includes brothers Pedro Tovar (lead vocalist) and Brian Tovar (bass). They are joined by friends Damian Pacheco (twelve-string guitar( and Ulises Gonzalez (acoustic guitar). Eslabon has nabbed many Billboard Latin Music Awards, including top Latin duo or group in 2021 and 2022.

Earlier this year, Gerardo Ortiz added his 13th No. 1 on the Regional Mexican Airplay chart with “Ahí No Era.” While his career spans more than 15 years, Ortiz’s younger brother, Kevin, follows right behind. Also a regional Mexican singer, Kevin was a new artist of the year finalist at the 2015 Billboard Latin Music Awards, and has collaborated with his older brother on many occasions.

Hailing from Colombian department Chocó, Goyo (real name: Gloria Martinez) and her younger brother Slow Mike (real name: Miguel Martinez) became a household name as part of the Latin Grammy-winning group ChocQuibTown, which also consisted of Goyo’s former partner, Carlos “Tostao” Valencia. In the band, Goyo sang and rapped while Slow produced.

In 2002, Louisiana-born sisters Hanna Nicole and Ashley Grace formed Latin pop duo Ha*Ash. In total, they have dropped six studio albums, including their 2022 effort Haashtag, and have collaborated with artists such as Los Angeles Azules, Leonel Garcia and Miguel Bosé. Three of their music videos have surpassed one billion views on YouTube: “Lo Aprendi de Ti,” “Destino o Casualidad” (with Melendi) and “Perdón, Perdón.”

A French-born musical duo of Cuban heritage, Ibeyi is composed of twin sisters Lisa-Kaindé and Naomi Diaz. The duo, who made their Coachella debut in 2016, fuse their French and Afro-Cuban heritage with jazz beats and traditional instruments. The name Ibeyi also celebrates the sisters’ identity, meaning “twins” in the Western African language Yoruba.

Born in Mexico City, siblings Jesse and Joy got on the radar with their 2005 hit “Espacio Sideral.” Together, they have brought to life other pop hits including “¡Corre!,” “Dueles” and “Ecos de Amor.” In 2007, they nabbed their first-ever Latin Grammy for best new artist. In total, they have six Latin Grammys and one Grammy. The duo is currently making the rounds with their 2022 album Clichés.

Las Villa, helmed by Colombian twins Laura and Lucía, made their debut in 2019 with “Nadita.” Signed to Warner Music Latina, the duo collaborated with Latin hitmaker Tainy on “Si La Vez,” featured on his 2020 Neon16 Tape album. Bringing an edgy and mystical sound to urban music, Las Villa has also teamed up with Wisin, Beele, Miky Woodz and more artists.

You’d think that because of their longevity and great chemistry that Zion y Lennox might be related, but they’re not. However, the latter does have a brother who’s also in the reggaetón realm: Lennox is brother to Luis Pizarro, who’s also known as Mackie Ranks, formerly of the urban duo Yaga y Mackie.

Brothers Poncho Jr. and Imanol Quezada have been performing for more than 10 years now, playing in buses, markets and at local parties in their native Coahuila, Mexico. But it wasn’t until 2018 that Los Dos Carnales got their big break — after being “discovered” by El Fantasma, who reached out to them to collaborate. Known for their distinct core norteño sound, Los Dos Carnales are signed to regional Mexican label AfinArte.

Born in Monterrey, Nuevo León, Los Esquivel — made up of brothers Sebastian and Eugenio — represents the new era of corridos, meshing it with an innovative trap sound. Both siblings also have their solo singing careers, but join forces once in a while as a duo. This year, Los Esquivel scored its first entry on Hot Latin Songs with “Alucin,” a collaboration with Marca Registrada (which landed at No. 49 on the tally dated Jan. 27), and signed a management deal with WK NXT, a division under WK Entertainment.

Los Temerarios are easily one of the most emblematic brothers in Latin music. Composed by brothers Adolfo Angel and Gustavo Angel, and their cousin Fernando Angel, the Mexican grupera band has placed 41 hits on Hot Latin Songs, including 17 tops 10s and four No. 1s. Last fall, the duo announced they were parting ways after over 40 years together, and are currently on their last tour together.

Luis Fonsi — best known for his 2017 megahit “Despacito,” which spent 16 weeks at No. 1 on the Hot 100 — has a talented younger brother named Jean Carlos, who’s also in the music space. The latter has released a handful of Latin pop tunes, including “Duele,” which hit No. 1 on Latin Pop Airplay in 2006, and is a member of the artist-producer duo Coastcity.

Singer-songwriter brothers Mauricio and Ricardo Montaner, sons of Latin pop artist Ricardo Montaner, have skyrocketed to fame after collaborating with artists such as Karol G, Lali, Thalia and Sebastian Yatra, to name a few. The urban-pop duo, who will soon release their new album Hotel Caracas, do not shy away from innovative fusions such as marrying alternative rock with futuristic urban melodies. Additionally, they are the older brothers of pop singer and actress Evaluna, who’s married to Camilo.

As teenagers, Manuel Turizo and his older brother, Julián, began creating music in their room. The former would write songs and sing them, and the latter would help in the composition, handle backup vocals and play the ukulele. In 2016, Manuel (then 16) and Julián (19) released their first song, “Una Lady Como Tú,” which peaked at No. 10 on the Latin Digital Song Sales chart in September 2017, becoming Turizo’s first Billboard chart entry.

Pepe Aguilar and oldest brother Antonio Aguilar, Jr., both sons of singers and actors Antonio Aguilar and Flor Silvestre, have led successful solo careers. Pepe hit No. 1 on the Top Latin Albums chart in 2003 with his album Y Tenerte Otra Vez. Almost 10 years prior, Pepe produced the 1994 debut album of his brother, Toda Mi Vida. The former is father of rising artists Angela and Leonardo Aguilar, and the latter of newcomer Majo Aguilar.

If their timeless 1984 hit “Olvídame y pega la vuelta” — a dramatic song detailing a breakup in real time — was any indication, you’d think that Pimpinela was a couple. However, the popular Argentine duo is composed by the talented brother and sister, Joaquín and Lucía Galán. Pimpinela was formed in 1981.

Before they each led their own successful solo careers as artists and producers, stepbrothers René “Residente” Pérez Joglar and Eduardo “Visitante” Cabra Martínez formed part of Puerto Rican alternative hip-hop duo Calle 13. Their half sister, Ileana Mercedes Cabra Joglar, artistically known as iLe, accompanied Calle 13 on backing vocals.

One of the most notable families in Latin music are the Quintanillas. Selena y Los Dinos — partially formed by the late Selena Quintanilla on vocals with her older siblings Abraham “A.B.” III (bass) and Suzette (drums), and managed by their father Abraham Quintanilla — singlehandedly revolutionized the Tejano genre in the late ’80s and early ’90s, with their fusion of Cumbia and Tex-Mex with rock, dance and R&B. Selena’s brother A.B. also produced and wrote some of her greatest solo hits, including “Amor Prohibido” and “Como La Flor.”

Venezuelan brother Servando and Florentino Primera once formed part of the popular ’90s salsa group Salserín before branching out. As a duo, the brothers achieved six entries on Hot Latin Songs, including their No. 1 hit “Una Fan Enamorada” in 1998, part of their debut album Los Primera. Still making music today, Servando & Florentino recently were a surprise guest on Karol G’s Mañana Será Bonito tour stop in Venezuela, where they all performed “De Sol a Sol.”

Simon & Simaria are a Brazilian duo formed by sisters Simone Mendes Rocha Diniz and Simaria Mendes Rocha Escrig, which fuses traditional forró rhythms with Latin pop and urban beats. The Latin Grammy-nominated act appeared on Karol G’s 2019 album Ocean, as featured guests on the track “La Vida Continuo.”

With his captivating romantic corrido sound, Xavi debuted on the Hot 100 last December with “La Diabla” and “La Víctima.” The former also reached top five on the Billboard Global 200 and Global Excl. U.S. charts. Meanwhile, his brother Fabio Capri is also making waves in the music industry with a more indie-pop, R&B approach. “Since we were kids, my brother and I used to make music,” Xavi previously told Billboard. “There came a time when we stopped and thank God music reconnected us.”