Christina Applegate Says She Wants to ‘Do Shots With Cher’ Amid MS Battle

Christina Applegate is sharing her bucket list.

The actress, who revealed her multiple sclerosis diagnosis in 2021, took to X (formerly known as Twitter) to share some of her current life goals. “There are things I want to do with the days I have left in life,” she wrote. “I want to work with Shirley MacLaine. And do shots with Cher!” 

However, Applegate assured she has plenty of life left to live. “And yes, my days are so big,” she added. “Just saying.”

Applegate has been open with her MS struggles over the years, particularly with how it’s been affecting her mentally. In the June 4 episode of her podcast, “MeSsy,” which she co-hosts with fellow MS survivor Jamie-Lynn Sigler, that she is “in a depression right now, which I don’t think I’ve felt for years.”

She added, “Like a breal, f–k it all, like real depression, where it’s kind of scaring me too a little bit because it feels really fatalistic. I’m trapped in this darkness right now that I haven’t felt like — I don’t even know how long, probably 20 something years. … I don’t enjoy living. I don’t enjoy things anymore.”

According to the World Health Organization, multiple sclerosis is a condition in which the immune system attacks the brain and spinal cord. Symptoms include “vision problems, tiredness, trouble walking and keeping balance, and numbness or weakness in the arms and legs.” While there is no cure for the condition, treatment can reduce symptoms and prevent future relapses.